Agrochemicals | Services

Toxicology

  • Operator, worker, bystander and resident exposure assessments:
    • Use of the EFSA guidance document and accompanying exposure model
    • Development of non-standard models (e.g. exposure by seed treatment)
    • Evaluation of dermal absorption studies
  • Assessment of the toxicological equivalence of active substances
  • Assessment of toxicological properties of active substances, impurities, metabolites (e.g. groundwater, plant metabolites) and plant protection products:
    • Evaluation of data from existing studies (e.g. intermediate in metabolic pathways structural similarities with the active substance or the active part)
    • Related QSAR based model calculations
    • Identification and supervision of appropriate toxicity studies